Epidemiological, clinical, and experimental research have clearly demonstrated strong association between serum lipids, lipoprotein levels and coronary artery disease. to investigate the risk factors of coronary artery disease in Korean, we
examined the
relationship between the level of lipoprotein components, other risk factors and the presence, severity of coronary artery disease in 48 patients and 40 normal healthy persons who underwent coronary angiography. In patient group, the level of
Lp(a),
triglyceride were significantly higher than control group (P<0.05, p<0.05), but HLD-C, Apo A-I, Apo a-I/B is significantly lower compared to control group. (P<0.05, P<0.05, P<0.05). In patient group, no significant correlation was observed
between
the
severity of coronary atherosclerosis and lipid level. For Lp(a), using cutoff point 35.0mg/dl, we obtained a sensitivity of 68% and specificity of 62%. For Apo-A-I, using cuttoff point of 120mg/dl, we obtained sensitivity and specificity of 50%
and
93%
respectively. For Apo B, using a cutoff point 90mg/dl, we obtained a sensitivity of 50% and specificity of 64%. For Apo A-I/B ratio, using a cutoff point 1.30, we obtained a sensitivity of 47% and specificity of 90% For HDL-C, using a cutoff
point
35.0mg/dl, we obtained a sensitivity of 47% and specificity of 90%. For HDL-C, using a cutoff point 35.0mg/dl, we obtained a sensitivity of 43% and specificity of 93%.
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